jueves, 13 de diciembre de 2007



¿What should I discuss with my healthcare provider before taking Orap?

Do not take Orap with any of the following medicines:
  • antibiotics including azithromycin (Zithromax), clarithromycin (Biaxin), erythromycin (Ery-Tab, E.E.S., E-Mycin, Eryc, PCE, and others), dirithromycin (Dynabac), and troleandomycin (TAO);
  • antifungal medicines including itraconazole (Sporanox) and ketoconazole (Nizoral);
  • protease inhibitors including amprenavir (Agenerase), ritonavir (Norvir), saquinavir (Fortovase, Invirase), indinavir (Crixivan), and nelfinavir (Viracept);
  • phenothiazines including chlorpromazine (Thorazine), fluphenazine (Prolixin), thioridazine (Mellaril), mesoridazine (Serentil), and trifluoperazine (Stelazine);
  • tricyclic antidepressants including amoxapine (Asendin), amitriptyline (Elavil, Endep), clomipramine (Anafranil), doxepin (Sinequan), desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil);
  • medicines for irregular heartbeats, including quinidine (Cardioquin, Quinora, Quinaglute, Quinidex), procainamide (Pronestyl, Procan SR), disopyramide (Norpace), propafenone (Rythmol), flecainide (Tambocor), amiodarone (Cordarone), and sotalol (Betapace);
  • nefazodone (Serzone);
  • zileuton (Zyflo); or
  • sertraline (Zoloft).

How should I take Orap?


Take Orap exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. Never take more of this medication than is prescribed for you. Do not consume grapefruit or grapefruit juice during treatment with Orap. Orap can interact with grapefruit products, and the interaction may have dangerous effects. Talk to your doctor before you stop taking this medication. It may be several weeks before you begin to feel better, and you may require continuous treatment for quite some time. A gradual reduction in dose may be recommended before stopping the medication. Store Orap at room temperature away from moisture and heat.